Neo-capsule tissue reactions in metal-on-metal hip arthroplasty.
作者： Wolf-Christoph Witzleb , Uwe Hanisch , Nicole Kolar , Frank Krummenauer , Klaus-Peter Guenther
DOI: 10.1080/17453670710013708
关键词: Wear resistance 、 Plasma cell 、 Artificial joints 、 Capsule 、 Hip arthroplasty 、 Lymphocytic infiltration 、 Medicine 、 Total hip replacement 、 Surgery 、 Pathology
摘要: Background Modern-generation metal-on-metal articulations have a high wear resistance and may therefore be able to improve the long-term performance of artificial joints. However, biological effects are still under debate. This study was undertaken review histopathological changes in neo-capsule tissues different hip arthroplasties.Methods Neo-capsule tissue samples from 46 hips with modern second-generation (39 resurfacings 7 non-cemented total replacements) variety failure mechanisms were examined histopathologically immunohistochemically.Results A distinct lymphocytic infiltration found all cases situ times more than months, consisting CD20-positive B-lymphocytes CD3positive T-lymphocytes sometimes thinly distributed CD138-positive plasma cells without dominant T-cell or cell infiltrates.Interpretation This has not been reported analyses o...
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