Prolongation of survival of an allograft by inhibiting complement activity

作者: Russell P. Rother , Hao Wang , Zheng Zhong

DOI:

关键词: Abo mismatchImmunologyBiomedical engineeringComplement activityMedicine

摘要: Methods of prolonging survival allotransplanted cells, tissues or organs are presented. These methods directed to administering the allotransplant recipient an inhibitor complement activity together with one more immunosuppressants. The is administered chronically. have been determined aid in preventing chronic rejection allografts. can additionally be used cases which has presensitized allograft there ABO mismatch between and recipient.

参考文章(45)
S. H. Sacks, J. R. Pratt, R. A. G. Smith, M. J. Hibbs, A. J. Laver, Effects of complement inhibition with soluble complement receptor-1 on vascular injury and inflammation during renal allograft rejection in the rat. American Journal of Pathology. ,vol. 149, pp. 2055- 2066 ,(1996)
Vincent H. L. Lee, Peptide and protein drug delivery M. Dekker. ,(1991)
Alfred L. M. Bothwell, Peter J. Sims, Cells expressing high levels of CD59 ,(1994)
Johan Beyers Van Den Bogaerde, David James Graham White, Inhibition of allograft and concordant xenograft rejection ,(1991)
Shiv Pillai, Abul K. Abbas, Andrew H. Lichtman, Cellular and Molecular Immunology ,(1994)
Robert C. Uschold, Robert John Strowe, Marian Gravel, Joseph Ferraro, Ashutosh Sharma, Benjamin Gasparello, William Thomas Antoshkiw, Antonio A. Bendek, Integrated system including medication delivery pen, blood monitoring device, and lancer ,(2000)