作者: Bruce E. Johnson , Seth M. Steinberg , Ruby Phelps , Margaret Edison , Stephen R. Veach
DOI: 10.1016/S0002-9343(88)80341-3
关键词: Incidence (epidemiology) 、 Lung cancer 、 Gynecology 、 Male patient 、 Clinical trial 、 Female patient 、 Internal medicine 、 Proportional hazards model 、 Medicine 、 Cancer 、 Non small cell
摘要: Purpose The incidence of lung cancer is rising in women the United States, and recent reports have suggested that female patients treated for small cell an improved survival compared with their male counterparts. In view these findings, we decided to determine if, our patient population, live longer than men if a higher proportion are entering trials. Patients methods therapeutic clinical trials from 1973 through 1986 at National Cancer Institute-Navy Medical Oncology Branch was evaluated similarly during same time period. Results (median 13 months versus 10 months). Cox proportional hazards modeling incorporating multiple prognostic factors indicated survived significantly ( p = 0.002) when adjustment other significant made. This advantage consistent both early late periods analyzed. addition, constituted larger later period, as nationwide. Conclusion We believe it will be important comparisons current older enrolled fewer control favorable factor sex.