Brain Protein Oxidation and Modification for Good or for Bad in Alzheimer’s Disease
作者： Rukhsana Sultana , D. Allan Butterfield
DOI: 10.1007/978-1-4419-7104-3_17
关键词: Endocrinology 、 Dementia 、 Disease 、 Postmortem tissue 、 Oxidative stress 、 Medicine 、 Synapse 、 Neuroscience 、 Senile plaques 、 Pathogenesis 、 Protein oxidation 、 Internal medicine
摘要: Alzheimer’s disease (AD) is the most common cause of dementia in elderly and characterized by senile plaques, neurofibrillary tangles, synapse loss, progressive neuronal deficits. There an abundance evidence suggesting that oxidative stress involved pathogenesis disease. Several investigations have revealed presence oxidation products proteins, lipids, DNA postmortem tissue from AD patients, indices are indicative increased stress. In present review we discuss role protein brain subjects with MCI.
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