作者: Yanfeng Luo , Juan Xing , Manping Lin
DOI: 10.1007/978-981-10-3554-8_5
关键词: Scaffold architecture 、 Biocompatibility 、 Nanofiber 、 Cell adhesion 、 Biomedical engineering 、 Protein adsorption 、 Materials science 、 Scaffold 、 Tissue repair
摘要: Protein adsorption on scaffolds is believed as the initial event happened before cell adhesion. The physiochemical properties of regulate protein which further modulates adhesion and subsequent responses, i.e. protein-cell interactions. In addition, provide a temporary physical support for cells so that their mechanical determine compatibility with surrounding environment adhered cells. Scaffolds-protein interactions, interactions dynamically interplay to control scaffolds’ biocompatibility. are essentially determined by themselves, which, however, have received insufficient attentions in 3D levels. Understanding fundamentals potentially helpful design. Fiber- or tube-reinforced featured improved altered architecture chemical compositions when compared unreinforced counterparts. Moreover, fibers tubes themselves parameters such fiber tube size alignment affect thus biocompatibility reinforced scaffolds. Therefore, this chapter, effects scaffold chemistries pore structure, fiber/tube were detailed, regulation cell/tissue responses was understood. biochemical cues included well.