Transmembrane crosstalk between the extracellular matrix and the cytoskeleton
作者： Benjamin Geiger , Alexander Bershadsky , Roumen Pankov , Kenneth M. Yamada
DOI: 10.1038/35099066
关键词:
摘要: Integrin-mediated cell adhesions provide dynamic, bidirectional links between the extracellular matrix and cytoskeleton. Besides having central roles in migration morphogenesis, focal related structures convey information across membrane, to regulate extracellular-matrix assembly, proliferation, differentiation, death. This review describes integrin functions, mechanosensors, molecular switches signal-transduction pathways activated integrated by adhesion, with a unifying theme being importance of local physical forces.
nature.com
sci-hub.se 参考文章(114)
Ottavio Cremona, Federico Caligaris-Cappio, Marina Schena, Gianluca Gaidano, Pier Carlo Marchisio, Mirella Gaboli, Luciana Bergui, Integrin distribution and cytoskeleton organization in normal and malignant monocytes. Leukemia. ,vol. 4, pp. 682- 687 ,(1990)
Dan P. Felsenfeld, Pamela L. Schwartzberg, Ana Venegas, Richard Tse, Michael P. Sheetz, Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src. Nature Cell Biology. ,vol. 1, pp. 200- 206 ,(1999) , 10.1038/12021
K.B. Kaplan, K.B. Bibbins, J.R. Swedlow, M. Arnaud, D.O. Morgan, H.E. Varmus, Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. The EMBO Journal. ,vol. 13, pp. 4745- 4756 ,(1994) , 10.1002/J.1460-2075.1994.TB06800.X
Masahiro Sokabe, Keiji Naruse, Xiaorui Sai, Activation of pp60(src) is critical for stretch-induced orienting response in fibroblasts Journal of Cell Science. ,vol. 112, pp. 1365- 1373 ,(1999) , 10.1242/JCS.112.9.1365
A.D. Bershadsky, I.S. Tint, A.A. Neyfakh, J.M. Vasiliev, Focal contacts of normal and RSV-transformed quail cells. Hypothesis of the transformation-induced deficient maturation of focal contacts. Experimental Cell Research. ,vol. 158, pp. 433- 444 ,(1985) , 10.1016/0014-4827(85)90467-7
K. Fukami, T. Endo, M. Imamura, T. Takenawa, alpha-Actinin and vinculin are PIP2-binding proteins involved in signaling by tyrosine kinase. Journal of Biological Chemistry. ,vol. 269, pp. 1518- 1522 ,(1994) , 10.1016/S0021-9258(17)42287-3
Sui Huang, Donald E. Ingber, The structural and mechanical complexity of cell-growth control. Nature Cell Biology. ,vol. 1, ,(1999) , 10.1038/13043
Carles Serra‐Pagès, NL Kedersha, L Fazikas, Q Medley, A Debant, M Streuli, None, The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. The EMBO Journal. ,vol. 14, pp. 2827- 2838 ,(1995) , 10.1002/J.1460-2075.1995.TB07282.X
L Kornberg, H.S. Earp, J.T. Parsons, M Schaller, R.L. Juliano, Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. Journal of Biological Chemistry. ,vol. 267, pp. 23439- 23442 ,(1992) , 10.1016/S0021-9258(18)35853-8
Wilkinson C, Curtis A, New depths in cell behaviour: reactions of cells to nanotopography. Biochemical Society symposium. ,vol. 65, pp. 15- 26 ,(1999)