Carriage of Neisseria meningitidis in Europe: a review of studies undertaken in the region.

摘要: Meningococcal conjugate vaccines induce herd protection by preventing nasopharyngeal meningococcal acquisition, which is a prerequisite for invasive disease. Thus, carriage epidemiology important in understanding relationships between and A literature search traced information on 27 EU countries. prevalence differed within countries, varying across age groups, serogroup distribution over time. Carriage increased during childhood, peaking 15–24-year-olds. While B was usually the dominant serogroupable carried serogroup, serogroups C, W-135 Y were also frequently carried. Current studies Europe are limited. New using standardized methods needed to improve our of disease etiology transmission, monitor impact populations.