Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression

摘要: We evaluated the effect of timing decompression spinal cord after compression 50 per cent diameter at fourth lumbar level in thirty purebred dogs. The dogs were divided into five groups six each on basis duration compression. Decompression was performed immediately (Group I), one hour II), hours III), twenty-four IV), or week V) Monitoring somatosensory evoked potentials, daily neurological examinations, and histological electron microscopic studies time autopsy for all Initially, paraplegic cord. that had immediate recovered ability to walk (grades 4 5, according Tarlov's system) as well control bowel bladder, potentials improved an average 85 72 cent, respectively. However, when lasted more, there no recovery progressive necrosis Somatosensory 29 Group III, 26 IV, 10 V. percentage by weeks significantly related (p < 0.0008).