Enhancement of the Stability of Insoluble Calcium Particles Using a Phospholipid Coating

作者: Naiyan Lu , Xuan Zhang , Jiaoyang Song , Xuejian Yu , Joe M. Regenstein

DOI: 10.1007/S11483-017-9484-5

关键词: AmphiphileCalciumPhospholipidSuspension (chemistry)Calcium carbonateBiochemistryChemical engineeringCoatingPrecipitation (chemistry)DissolutionMaterials science

摘要: Calcium is one of the most important elements in human body. Insoluble calcium particles are often used calcium-fortified food products, such as milk, dairy beverages or protein powders. However, their suspension may be unstable leading to precipitation products. In this study, three different kinds insoluble particles, i.e. hydroxyapatite (HA), tricalcium phosphate (TCP) and carbonate (CaCO3) were coated with amphiphilic phospholipids using a solvent-exchange method. Suspension stability these was effectively improved phospholipid coating, especially for HA TCP, more on surface two than CaCO3. Phospholipid coating increased electrostatic repulsions between preventing from aggregating precipitating. addition, digestibility phospholipid-coated tested simulated gastric juice, dissolution time prolonged through coating.

参考文章(34)
Lijie Wen, Dasong Liu, Jinhua Hu, Xiaoming Liu, Joe M. Regenstein, Peng Zhou, Variation of insoluble calcium salts in protein adsorption and suspension stability when dispersed in sodium caseinate solutions Food Hydrocolloids. ,vol. 52, pp. 311- 316 ,(2016) , 10.1016/J.FOODHYD.2015.07.002
Advanced dairy chemistry australasian database conference. ,(2009) , 10.1007/978-0-387-84865-5
Kamil P Drapala, Mark AE Auty, Daniel M Mulvihill, James A O'Mahony, None, Influence of lecithin on the processing stability of model whey protein hydrolysate‐based infant formula emulsions International Journal of Dairy Technology. ,vol. 68, pp. 322- 333 ,(2015) , 10.1111/1471-0307.12256
Robert P Heaney, Protein and calcium: antagonists or synergists? The American Journal of Clinical Nutrition. ,vol. 75, pp. 609- 610 ,(2002) , 10.1093/AJCN/75.4.609
Martim Victor Hammes, Alexandre Hahn Englert, Caciano Pelayo Zapata Noreña, Nilo Sérgio Medeiros Cardozo, Study of the influence of soy lecithin addition on the wettability of buffalo milk powder obtained by spray drying Powder Technology. ,vol. 277, pp. 237- 243 ,(2015) , 10.1016/J.POWTEC.2015.02.047
Dick THM Sijm, Manuela Haller, Joop AJ Faber, S Marca Schrap, None, Influence of carrier and bactericide on sorption coefficients of hydrophobic organic compounds for two lake sediments Water Research. ,vol. 32, pp. 3134- 3142 ,(1998) , 10.1016/S0043-1354(98)00061-X
Shobha N Bhattachar, James A Wesley, Ann Fioritto, Peter J Martin, Suresh R Babu, Dissolution testing of a poorly soluble compound using the flow-through cell dissolution apparatus. International Journal of Pharmaceutics. ,vol. 236, pp. 135- 143 ,(2002) , 10.1016/S0378-5173(02)00027-3
J. R. Nordlund, C. F. Schmidt, S. N. Dicken, T. E. Thompson, Transbilayer distribution of phosphatidylethanolamine in large and small unilamellar vesicles. Biochemistry. ,vol. 20, pp. 3237- 3241 ,(1981) , 10.1021/BI00514A039
C. Jeffrey Brinker, Yunfeng Lu, Alan Sellinger, Hongyou Fan, Evaporation-Induced Self-Assembly: Nanostructures Made Easy** Advanced Materials. ,vol. 11, pp. 579- 585 ,(1999) , 10.1002/(SICI)1521-4095(199905)11:7<579::AID-ADMA579>3.0.CO;2-R
Juliane Hellhammer, Ali‐Reza Waladkhani, Torsten Hero, Claudia Buss, Effects of milk phospholipid on memory and psychological stress response British Food Journal. ,vol. 112, pp. 1124- 1137 ,(2010) , 10.1108/00070701011080258