Chemical composition and cholinesterase inhibition of essential oils of three chemotypes from Croton zehntneri
作者： Telma L. G Lemos , Paulo N. Bandeira , Luciana M. Bertini , Elaine F. Furtado , Hélcio S. Santos
DOI:
关键词: Chemotype 、 Cholinesterase inhibition 、 Biology 、 Chemical composition 、 Eugenol 、 Euphorbiaceae 、 Isoeugenol 、 Croton 、 Botany 、 Medicinal plants
摘要: Croton zehntneri Pax. & K. Hoffm. (Euphorbiaceae) is an aromatic plant native of the northeaster region Brazil; and popularly known as “canela de cunha”. The chemical composition essential oils from leaves, stalks roots three chemotypes C. obtained by hydrodistillation were analyzes GC-MS. E-anethole, was main component in all plants parts chemotype 1. While phenylpropanoids stragole, eugenol, Z-methyl isoeugenol E-methyl major 2 3, respectively. On TLC compounds showed acetylcholine esterase inhibitory effect.
cabdirect.org参考文章(31)
E. R. Silveira, J. D. McChesney, ent-Clerodanes of Croton sonderianus. Fitoterapia. ,vol. 61, pp. 172- 175 ,(1990)
Antonio Salatino, Maria L. Faria Salatino, Giuseppina Negri, Traditional uses, chemistry and pharmacology of Croton species (Euphorbiaceae) Journal of the Brazilian Chemical Society. ,vol. 18, pp. 11- 33 ,(2007) , 10.1590/S0103-50532007000100002
George L. Ellman, K.Diane Courtney, Valentino Andres, Robert M. Featherstone, A new and rapid colorimetric determination of acetylcholinesterase activity Biochemical Pharmacology. ,vol. 7, pp. 88- 95 ,(1961) , 10.1016/0006-2952(61)90145-9
A. N. Coelho-de-Souza, D. N. Criddle, J. H. Leal-Cardoso, Selective modulatory effects of the essential oil of Croton zehntneri on isolated smooth muscle preparations of the guinea-pig Phytotherapy Research. ,vol. 12, pp. 189- 194 ,(1998) , 10.1002/(SICI)1099-1573(199805)12:3<189::AID-PTR222>3.0.CO;2-S
Pedro Rocha Barbosa, Miguel Fascio, Dirceu Martins, Maria L Silva Guedes, Nidia Franca Roque, Triterpenes of Croton betulaster (Euphorbiaceae) Biochemical Systematics and Ecology. ,vol. 31, pp. 307- 308 ,(2003) , 10.1016/S0305-1978(02)00145-X
Maria Aparecida M Maciel, Angelo C Pinto, Alberto C Arruda, Sônia GSR Pamplona, Frederico A Vanderlinde, Antonio J Lapa, Aurea Echevarria, Noema F Grynberg, Ilce MS Côlus, Rômulo AF Farias, Angelica M Luna Costa, Vietla SN Rao, None, Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara. Journal of Ethnopharmacology. ,vol. 70, pp. 41- 55 ,(2000) , 10.1016/S0378-8741(99)00159-2
Marize T.L.P Peres, Franco Delle Monache, Alexandre Bella Cruz, Moacir G Pizzolatti, Rosendo A Yunes, Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae) Journal of Ethnopharmacology. ,vol. 56, pp. 223- 226 ,(1997) , 10.1016/S0378-8741(97)00039-1
S. Savelev, E. Okello, N.S.L. Perry, R.M. Wilkins, E.K. Perry, Synergistic and antagonistic interactions of anticholinesterase terpenoids in Salvia lavandulaefolia essential oil Pharmacology, Biochemistry and Behavior. ,vol. 75, pp. 661- 668 ,(2003) , 10.1016/S0091-3057(03)00125-4
Federica Menichini, Rosa Tundis, Monica R. Loizzo, Marco Bonesi, Mariangela Marrelli, Giancarlo A. Statti, Francesco Menichini, Filomena Conforti, Acetylcholinesterase and butyrylcholinesterase inhibition of ethanolic extract and monoterpenes from Pimpinella anisoides V Brig. (Apiaceae) Fitoterapia. ,vol. 80, pp. 297- 300 ,(2009) , 10.1016/J.FITOTE.2009.03.008
Melanie-Jayne R. Howes, Peter J. Houghton, Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function. Pharmacology, Biochemistry and Behavior. ,vol. 75, pp. 513- 527 ,(2003) , 10.1016/S0091-3057(03)00128-X