作者: Geanne KN Santos , Kamilla A Dutra , Camila S Lira , Bheatriz N Lima , Thiago H Napoleão
DOI: 10.3390/MOLECULES191016573
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摘要: Although numerous reports are available concerning the larvicidal potential of essential oils, very few investigations have focused on their mechanisms action. In present study, we investigated chemical composition leaf oil Croton rhamnifolioides during storage and its effects oviposition survival larvae dengue fever mosquito Aedes aegypti. addition, established a possible mechanism action for activity oil. GC-MS analyses revealed marked differences in that had been freshly isolated sample stored sealed amber-glass vial under refrigeration three years. However, both fresh exhibited substantial activities with LC50 values 122.35 89.03 ppm, respectively, deterrent against gravid females at concentrations 50 100 µg·mL−1. These results demonstrate effect was unchanged years even though altered. Hence, could be used preparation commercial products. observed trypsin-like inhibited vitro by C. rhamnifolioides, suggesting may associated inhibition this enzyme.