Epithelial skin stem cells

作者: Tudorita Tumbar

DOI: 10.1016/S0076-6879(06)19004-7

关键词: BiologyCell biologyAmniotic epithelial cellsEpidermis (botany)Endothelial stem cellStem cellHair follicleImmunologyAmniotic stem cellsDermisAdult stem cell

摘要: Major progress in understanding epithelial skin stem cells has been accomplished. This possible by developing new methods for labeling, tracking, isolating, and characterizing enriched populations of cells. chapter summarizes vivo vitro assays that are currently employed to analyze Despite progress, the definition a cell is functional one. Unambiguous identification intact tissue still not possible. These limitations hamper molecular studies aimed at unraveling cellular mechanisms operating compartment. emphasizes current analyzing hair follicle cells, as opposed other compartments, because most intensively studied up date.

参考文章(181)
Dunnwald M, Bickenbach, Epidermal stem cells: characteristics and use in tissue engineering and gene therapy. Advances in Dermatology. ,vol. 16, pp. 159- ,(2000)
Fuchs E, Beauty is skin deep: the fascinating biology of the epidermis and its appendages Harvey Lectures. ,vol. 94, pp. 47- 77 ,(1998)
Gf Odland, Structure of the skin Physiology, biochemistry, and molecular biology of the skin. ,vol. 1, pp. 3- 62 ,(1991)
Lowell A. Goldsmith, Physiology, biochemistry, and molecular biology of the skin Oxford University Press. ,(1991)
Ariane Rochat, Yann Barrandon, Regeneration of Epidermis from Adult Keratinocyte Stem Cells Essentials of Stem Cell Biology (Second Edition). pp. 551- 560 ,(2009) , 10.1016/B978-0-12-374729-7.00061-5
C T Arsenault, A F Silver, H B Chase, Early anagen initiated by plucking compared with early spontaneous anagen. pp. 265- ,(1969)
Rebekah L. Waikel, Yasuhiro Kawachi, Patricia A. Waikel, Xiao-Jing Wang, Dennis R. Roop, Deregulated expression of c-Myc depletes epidermal stem cells. Nature Genetics. ,vol. 28, pp. 165- 168 ,(2001) , 10.1038/88889
Allan Spradling, Daniela Drummond-Barbosa, Toshie Kai, Stem cells find their niche Nature. ,vol. 414, pp. 98- 104 ,(2001) , 10.1038/35102160
Vladimir A. Botchkarev, Natalia V. Botchkareva, Wera Roth, Motonobu Nakamura, Ling-Hong Chen, Wiebke Herzog, Gerd Lindner, Jill A. McMahon, Christoph Peters, Roland Lauster, Andrew P. McMahon, Ralf Paus, Noggin is a mesenchymally derived stimulator of hair-follicle induction Nature Cell Biology. ,vol. 1, pp. 158- 164 ,(1999) , 10.1038/11078
Alea A. Mills, Binhai Zheng, Xiao-Jing Wang, Hannes Vogel, Dennis R. Roop, Allan Bradley, p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. ,vol. 398, pp. 708- 713 ,(1999) , 10.1038/19531