NADPH diaphorase-positive neurons in the lizard hippocampus: a distinct subpopulation of GABAergic interneurons.

摘要: We analyzed the distribution and light-microscopic features of NADPH diaphorase-containing structures in lizard hippocampus, likely to correspond nitric oxide synthase-containing cells fibers, thus release oxide. also studied co-localization diaphorase with neurotransmitter GABA, calcium-binding protein parvalbumin, neuropeptide somatostatin, order examine whether putative oxide-synthesizing neurons represent a different subpopulation GABA cells, on which authors recently reported lizards. parvalbumin or somatostatin mice ascertain characteristics this population reptiles parallel situation mammals. Most positive were stained Golgi-like manner plexiform layers hippocampus morphologies ranging from bipolar multipolar. Co-localization was 100%, diaphorase-positive did not contain somatostatin. The results indicate that distinct interneurons hippocampus. Two types fibers described layers: one type bearing thick varicosities, other thinner ones. discuss possibility at least part arise hypothalamic aminergic nucleus contacting third ventricle, periventricular organ. radial glia almost completely formed typical end-feet both pia around capillaries. study confirm capacity for synthesizing is linked determined set neuronal markers depending specific brain region, they provide new resemblances between hippocampal regions classes vertebrates.