An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.
作者： S Treeprasertsuk , K Chalermrut , S Srivilairit , U Silachamroon , S Krudsood
DOI:
关键词: Surgery 、 Group B 、 Medicine 、 Artesunate 、 Malaria 、 Mefloquine 、 Internal medicine 、 Plasmodium falciparum 、 Clinical trial 、 Randomized controlled trial 、 Piperaquine
摘要: The efficacy and safety of Artecom were assessed in an open randomized trial adults presenting with acute, uncomplicated Plasmodium falciparum malaria Thailand. Three hundred fifty-two patients randomly enroled at the ratio 2:1 into group A:B received (group A) standard combination artesunate mefloquine B) respectively. All had rapid initial clinical parasitological responses. There no significant differences fever clearance time parasite between two groups. 28-day cure rates high as 97% both was effective well-tolerated artesunate-mefloquine, current treatment this area multidrug-resistant P. malaria.
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