MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2.
作者： Pu Zhang , Huiyuan Bai , Gentao Liu , Heyong Wang , Feng Chen
DOI: 10.1016/J.TOXLET.2015.02.018
关键词: RHOA 、 Vimentin 、 Cell cycle 、 Epithelial–mesenchymal transition 、 Biology 、 Cancer research 、 Focal adhesion assembly 、 microRNA 、 Stress fiber 、 Melanoma
摘要: … of FAK, Src and RhoA and expression of EMT markers. Our results revealed that EF24 exposure inhibited the expression of HMGA2 in melanoma cells, suggesting that EF24 could be a …
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