Oral diseases associated with hepatitis C virus infection. Part 1. Sialadenitis and salivary glands lymphoma

摘要: Morbidity associated with hepatitis C virus (HCV) infection is due not only to the sequelae of chronic liver disease, but also a variety extraheaptic manifestations (EHM). Some most frequently reported EHM HCV involves oral region predominantly or exclusively and they are topics this 2-part review. The current part 1 discusses evidences on association salivary glands disorders HCV. HCV- infected patients may have histological signs Sjogren-like sialadenitis mild even absent clinical symptoms. However, pathogenetic role in Sjogren Syndrome (SS) development characteristics distinguishing classic SS from HCV-related still an issue. It unclear if cause disease mimicking primary directly responsible for specific subset patients. Notably, some present triple between HCV, SS-like gland lymphoma be involved lymphomagenesis. risk having particularly high mixed cryoglobulinemia. Little attention has been paid effects anti-HCV treatment development.