Metabolism and Acute Toxicity of Volatile Anesthetics
作者： V. Hempel , W. Heipertz , H-V Gärtner , M. Schmelzle
DOI: 10.1007/978-3-642-71232-6_6
关键词: Acute toxicity 、 Halothane 、 Hepatic necrosis 、 Hepatic malignancy 、 Pharmacology 、 CCL4 、 Metabolism 、 Volatile anesthetic 、 Chemistry 、 Anesthetic
摘要: It is well documented that the halogenated methane derivatives CCl4 and to a lesser extent CHCl3, therefore also anesthetic chloroform, which was used until into sixties, are hepatotoxic [10]. There good reason suspect halothane might occasionally cause liver reactions leading lethal hepatic necrosis [5].
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