Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends.
作者： Zhu Zhu , Woo-Hyun Chung , Eun Yong Shim , Sang Eun Lee , Grzegorz Ira
DOI: 10.1016/J.CELL.2008.08.037
关键词: Molecular biology 、 Sgs1 、 Exonuclease 1 、 Helicase 、 Exonuclease 、 MRX complex 、 MRN complex 、 Homologous recombination 、 Biology 、 DNA repair
摘要: … ssDNA is created over time on one side of a DSB in the sgs1Δ exo1Δ mutant. The first 100 nucleotides … 10% of cells processed DSB ends beyond 100 or 200 nucleotides, respectively (…
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Monica Riley, Karl Drlica, The Bacterial Chromosome ,(1990)
C.I. White, J.E. Haber, Intermediates of recombination during mating type switching in Saccharomyces cerevisiae. The EMBO Journal. ,vol. 9, pp. 663- 673 ,(1990) , 10.1002/J.1460-2075.1990.TB08158.X
Kyungjae Myung, Abhijit Datta, Clark Chen, Richard D. Kolodner, SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nature Genetics. ,vol. 27, pp. 113- 116 ,(2001) , 10.1038/83673
E L Ivanov, N Sugawara, C I White, F Fabre, J E Haber, Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Molecular and Cellular Biology. ,vol. 14, pp. 3414- 3425 ,(1994) , 10.1128/MCB.14.5.3414
Paul M. Watt, Edward J. Louis, Rhona H. Borts, Ian D. Hickson, SGS1, a Homologue of the Bloom's and Werner's Syndrome Genes, Is Required for Maintenance of Genome Stability in Saccharomyces cerevisiae Genetics. ,vol. 144, pp. 935- 945 ,(1996) , 10.1093/GENETICS/144.3.935
Sung-Ho Bae, Kwang-Hee Bae, Jung-Ae Kim, Yeon-Soo Seo, RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes Nature. ,vol. 412, pp. 456- 461 ,(2001) , 10.1038/35086609
Sang Eun Lee, Debra A Bressan, John HJ Petrini, James E Haber, Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenance DNA Repair. ,vol. 1, pp. 27- 40 ,(2002) , 10.1016/S1568-7864(01)00003-9
Ping-Yao Zeng, Christopher R. Vakoc, Zhu-Chu Chen, Gerd A. Blobel, Shelley L. Berger, In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. BioTechniques. ,vol. 41, pp. 694- 698 ,(2006) , 10.2144/000112297
Steven Raynard, Wendy Bussen, Patrick Sung, A Double Holliday Junction Dissolvasome Comprising BLM, Topoisomerase IIIα, and BLAP75 * Journal of Biological Chemistry. ,vol. 281, pp. 13861- 13864 ,(2006) , 10.1074/JBC.C600051200
Sanie Mnaimneh, Armaity P Davierwala, Jennifer Haynes, Jason Moffat, Wen-Tao Peng, Wen Zhang, Xueqi Yang, Jeff Pootoolal, Gordon Chua, Andres Lopez, Miles Trochesset, Darcy Morse, Nevan J Krogan, Shawna L Hiley, Zhijian Li, Quaid Morris, Jörg Grigull, Nicholas Mitsakakis, Christopher J Roberts, Jack F Greenblatt, Charles Boone, Chris A Kaiser, Brenda J Andrews, Timothy R Hughes, Exploration of essential gene functions via titratable promoter alleles Cell. ,vol. 118, pp. 31- 44 ,(2004) , 10.1016/J.CELL.2004.06.013