作者: P. He , S. Wada , N. Watanabe , K. Sugiyama
DOI: 10.1111/J.1365-2621.2000.TB15951.X
关键词: Theanine 、 Rat liver 、 Chemistry 、 Active compound 、 Pharmacology 、 Glutamic acid 、 Liver injury 、 Green tea 、 Galactosamine 、 Biochemistry 、 Glutamine
摘要: : This study was conducted to isolate the constituent, which had a preventive effect on D-galactosamine-induced rat liver injury, from 70% ethanol-soluble fraction of Japanese green tea. Theanine (glutamic acid γ-ethylamide) identified as active compound, and injury-preventive theanine dose-dependent. L-Glutamic γ-ethyl ester, but not glutamine, also brought about significantly injury when added diet at equimolar levels that 1% theanine. The results indicate is one effective constituents tea in preventing injury.