Clinically Relevant Radioactive Dose Formulation of 177Lu‐Labeled Cetuximab‐Fab Fragment for Potential Use in Cancer Theranostics

作者: Rubel Chakravarty , Nanda Rohra , Sudipta Chakraborty , Ratnesh Jain , Haladhar Dev Sarma

DOI: 10.1002/SLCT.201702224

关键词: Cancer researchCancerCetuximabFragment (computer graphics)Chemistry

摘要:

参考文章(36)
Aaron L. Nelson, Antibody fragments mAbs. ,vol. 2, pp. 77- 83 ,(2010) , 10.4161/MABS.2.1.10786
Francesco Caponigro, Roberta Formato, Michele Caraglia, Nicola Normanno, Rosario Vincenzo Iaffaioli, Monoclonal antibodies targeting epidermal growth factor receptor and vascular endothelial growth factor with a focus on head and neck tumors. Current Opinion in Oncology. ,vol. 17, pp. 212- 217 ,(2005) , 10.1097/01.CCO.0000159623.68506.CF
S. Shi, H. Orbay, Y. Yang, S. A. Graves, T. R. Nayak, H. Hong, R. Hernandez, H. Luo, S. Goel, C. P. Theuer, R. J. Nickles, W. Cai, PET Imaging of Abdominal Aortic Aneurysm with 64Cu-Labeled Anti-CD105 Antibody Fab Fragment The Journal of Nuclear Medicine. ,vol. 56, pp. 927- 932 ,(2015) , 10.2967/JNUMED.114.153098
Wouter A. Breeman, Katy van der Wansem, Bert F. Bernard, Arthur van Gameren, Jack L. Erion, Theo J. Visser, Eric P. Krenning, M. de Jong, The addition of DTPA to [177Lu-DOTA0,Tyr3]octreotate prior to administration reduces rat skeleton uptake of radioactivity. European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 30, pp. 312- 315 ,(2003) , 10.1007/S00259-002-1054-4
Chetan Yewale, Dipesh Baradia, Imran Vhora, Sushilkumar Patil, Ambikanandan Misra, Epidermal growth factor receptor targeting in cancer: a review of trends and strategies. Biomaterials. ,vol. 34, pp. 8690- 8707 ,(2013) , 10.1016/J.BIOMATERIALS.2013.07.100
Sofia Agelaki, Vassilis Georgoulias, Epidermal growth factor receptor inhibitors in the treatment of non-small cell lung cancer. Expert Opinion on Emerging Drugs. ,vol. 10, pp. 855- 874 ,(2005) , 10.1517/14728214.10.4.855
Ashutosh Dash, Maroor Raghavan Ambikalmajan Pillai, Furn F. Knapp, Production of 177 Lu for Targeted Radionuclide Therapy: Available Options Nuclear Medicine and Molecular Imaging. ,vol. 49, pp. 85- 107 ,(2015) , 10.1007/S13139-014-0315-Z
Weibo Cai, Kai Chen, Lina He, Qizhen Cao, Albert Koong, Xiaoyuan Chen, Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 34, pp. 850- 858 ,(2007) , 10.1007/S00259-006-0361-6
Amanda C. Freise, Anna M. Wu, In vivo Imaging with Antibodies and Engineered Fragments Molecular Immunology. ,vol. 67, pp. 142- 152 ,(2015) , 10.1016/J.MOLIMM.2015.04.001
Jaya Shukla, Rakhee Vatsa, Nitasha Garg, Ankit Watts, BhagwantR Mittal, Priya Bhusari, Quality control of positron emission tomography radiopharmaceuticals: An institutional experience. Indian Journal of Nuclear Medicine. ,vol. 28, pp. 200- ,(2013) , 10.4103/0972-3919.121963