Pseudomonas burn wound sepsis. I

作者: David Davis , Arthur D. Mason , John A. Moncrief , Carl Teplitz

DOI: 10.1016/S0022-4804(64)80026-3

关键词: BiologyGranulation tissuePathologyPathogenesisLeukopeniaBone marrow examinationBacteremiaSepsisStaphylococcusVasculitis

摘要: Summary The bacteriologic and clinicopathologic features of experimental Pseudomonas burn wound sepsis display an orderly sequence progression. There is initial supraeschar intrafollicular (hair) bacillary localization followed by more widespread intraeschar colonization. By the fourth fifth days, bacilli have invaded to junction burned viable tissue, at this time a low grade bacteremia becomes evident. Bacteria then invade zone granulation tissue. During terminal phase disease, bacterial invasion front destroys tissue invades deeper tissues. This associated with rise in pseudomonad count blood stream appearance visceral hematogenous lesions, leukopenia hypothermia. lesions not infrequently show vasculitis similar that seen human disease. details findings rat are discussed relation its counterpart.

参考文章(7)
Simon Sevitt, Burns : pathology and therapeutic applications Butterworth. ,(1957)
HARREL L. WALKER, ARTHUR D. MASON, LT COL GILBERT L. RAULSTON, SURFACE INFECTION WITH PSEUDOMONAS AERUGINOSA. Annals of Surgery. ,vol. 160, pp. 297- 305 ,(1964) , 10.1097/00000658-196408000-00019
Kehl Markley, Gabriel Gurmendi, Pablo Mori Chaver, Augusto Bazan, Fatal Pseudomonas septicemias in burned patients. Annals of Surgery. ,vol. 145, pp. 175- 181 ,(1957) , 10.1097/00000658-195702000-00005
Erwin R. Rabin, Charles D. Graber, Edward H. Vogel, Richard A. Finkelstein, Wilfred A. Tumbusch, Fatal pseudomonas infection in burned patients. A clinical, bacteriologic and anatomic study. The New England Journal of Medicine. ,vol. 265, pp. 1225- 1231 ,(1961) , 10.1056/NEJM196112212652501
John Q. Griffith, Edmond J. Farris, The rat in laboratory investigation The American Journal of the Medical Sciences. ,vol. 204, pp. 289- ,(1942) , 10.1097/00000441-194208000-00028
C. Teplitz, G. L. Raulston, H. L. Walker, A. D. Mason, J. A. Moncrief, SPONTANEOUS HEMATOGENOUS PSEUDOMONAS PYELONEPHRITIS IN RATS. The Journal of Infectious Diseases. ,vol. 114, pp. 75- 79 ,(1964) , 10.1093/INFDIS/114.1.75
William Margaretten, Hisayo Nakai, Benjamin H. Landing, Significance of selective vasculitis and the "bone-marrow" syndrome in Pseudomonas septicemia. The New England Journal of Medicine. ,vol. 265, pp. 773- 776 ,(1961) , 10.1056/NEJM196110192651603