The effect of peripheral chemodenervation on the ventilatory response to potassium

作者: D.M. Band , R.A.F. Linton , R. Kent , F.L. Kurer

DOI: 10.1016/0034-5687(85)90105-7

关键词: FissipediaPeripheral chemoreceptorsRespiratory systemAnesthesiaPotassiumCATSChemodenervationChemistryBreathingRespiration

摘要: Abstract The present experiments were designed to test the hypothesis that increase in plasma potassium which occurs during exercise acts as a stimulus respiration via peripheral chemoreceptors. effect of intravenous infusion KCl on ventilation was measured anaesthetised cats while they loaded with CO 2 intravenously bubble gas exchanger. Ventilation K + compared immediately before ‘intact’ and peripherally chemodenervated cats. In group there highly significant approximately 25% (+253±22ml/min, P concentration. results these indicate infusions stimulate this is abolished by chemodenervation.

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