A comparison between muscle function and body composition in anorexia nervosa: the effect of refeeding.

摘要: Skeletal muscle function, body composition (total nitrogen and total potassium) standard parameters of nutritional assessment were measured in six severely depleted patients with primary anorexia nervosa, both on admission during oral refeeding. The function the adductor pollicis was assessed by electrical stimulation ulnar nerve. On markedly abnormal nervosa (n = 6) compared normal subjects 22), a significant increase force contraction at 10 Hz, mean +/- SEM 48.0 3.7% 28.8 1.2%, respectively (p less than 0.001). There slowing maximal relaxation rate, 6.6 0.6% 9.6 0.2%, 0.001) increased fatigue 18.6 5.9% 3.5 0.8%, 0.01). Initially, serum albumin (4.0 0.1 g/dl), although there evidence severe depletion somatic protein stores, low creatinine-height index. Within 4 wk refeeding, rate fatigability restored to normal, within 8 all normal. During study only 13% still 19.4% below predicted nitrogen, whereas potassium 32% fat 46%. Normalization may be related restoration electrolytes rather repletion nitrogen.