Co-infection with HIV and TB: double trouble

摘要: Co-infection with HIV and Mycobacterium tuberculosis is common, particularly in the developing world. Tuberculosis (TB) commonest co-infection HIV-positive individuals, who are at increased risk of both reactivation latent infection acquisition new infection. As degree immunosuppression increases, risks TB disease also increase. The patho-physiology, clinical picture, differential diagnosis diagnostic tests discussed, together interactions between antiretroviral therapy anti-tuberculous chemotherapy. Indications for chemoprophylaxis vaccination against reviewed.