Reduced polymorphism in the chimpanzee semen coagulating protein, semenogelin I.

摘要: The semen of many primate species coagulates into a mating plug believed to prevent the sperm subsequent events from accessing ova. texture coagulum varies among species: semisoft mass in humans firm chimpanzees. In humans, component coagulum, semenogelin I, also inhibits motility. We tested hypothesis that polymorphism and divergence at I differ hominoid with different systems. Sequence data for locus were obtained 12 10 chimpanzees, 7 gorillas, 1 bonobo. Mitochondrial D-loop collected subset individuals assess levels variation an unlinked locus. HKA tests using sequence revealed significant reduction consistent predictions selective sweep this This result was supported by independent putatively neutral literature. Humans show similar trend toward reduced polymorphism, although only marginally significant. Gorilla evidence functional loss locus, indicated stop codons within putative open reading frame as well high polymorphism. Elevated K a/K s ratios Pan–Homo clade suggest history positive selection I. Our results there is relationship between intensity competition strength Darwinian on seminal protein