Electrocardiographic features of inherited diseases that predispose to the development of cardiac arrhythmias, long QT syndrome, arrhythmogenic right ventricular cardiomyopathy/dysplasia, and Brugada syndrome.

摘要: Abstract Analysis of the 12-lead electrocardiogram (ECG) provides important diagnostic and prognostic information in long QT syndrome. The clinical diagnosis syndrome is determined by presence a QTc≥0.44 sec. A normal QTc does not exclude family member from being genetic carrier. ECG patterns depolarization, ST segment shape T-wave can provide clues as to affected gene, particularly conjunction with precipitating causes syncope or cardiac events. In arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D), typical pattern consists inversion beyond lead V 1 . Evidence parietal block manifest QRS duration ≥110 msec longer then left precordial leads. slow fractionated conduction present epsilon waves. signal averaged may show exceedingly low late potentials. Information regarding risk sudden death also be obtaioned ECG. changes alone combination strong evidence for ARVC/D helps differentiate outflow tract (RVOT) tachycardia. Brugada elevation This abnormality dormant elicited administration drugs that cause Na channel blockade, such ajmaline type 1a 1C antiarrhythmic drugs. Individuals who do have findings at baseline but this induced are death. Further stratification obtained asymptomatic patients if fibrillation electrophysiological study.