The effect of purified micronized flavonoid fraction on the healing of anastomoses in the colon in rats.
作者： Aydin Ïnan , Meral Şen , Cemile Koca , Ayhan Akpinar , Cenap Dener
DOI: 10.1007/S00595-006-3251-4
关键词: Surgical oncology 、 Surgery 、 Anastomosis 、 Large intestine surgery 、 Major complication 、 Flavonoid 、 Medicine 、 Colonic anastomosis 、 Anastomotic leakage
摘要: Purpose Anastomotic leakage of colonic and rectal anastomoses is a major complication after large intestine surgery. Many factors influence the healing colon anastomoses. Flavonoids have been recognized for centuries as physiologically active constituents that are used to treat human diseases. We studied effects clinically used, micronized, purified flavonoid fraction on anastomosis in rats.
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Damon M, Flandre O, Michel F, Labrid C, Perdrix L, Crastes de Paulet A, Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2 alpha and thromboxane B2 release and histological changes. Drug Research. ,vol. 37, pp. 1149- 1153 ,(1987)
A C van der Ham, W J Kort, A M Bijma, F J Zijlstra, M A Vermeer, J Jeekel, Eicosanoid profile of healing colon anastomosis and peritoneal macrophages in the rat. Gut. ,vol. 31, pp. 807- 811 ,(1990) , 10.1136/GUT.31.7.807
M. Seyer-Hansen, T.T. Andreassen, H. Christensen, H. Oxlund, Effect of experimental diabetes and growth hormone administration on the strength of colonic anastomoses in rats. European Surgical Research. ,vol. 31, pp. 419- 428 ,(1999) , 10.1159/000008721
Lilian McGregor, Michel Bellangeon, Elsa Chignier, Laurence Lerond, Cecile Rousselle, John L McGregor, Effect of a micronized purified flavonoid fraction on in vivo platelet functions in the rat. Thrombosis Research. ,vol. 94, pp. 235- 240 ,(1999) , 10.1016/S0049-3848(98)00216-3
Ronald J. Korthuis, Dean C. Gute, Adhesion Molecule Expression in Postischemic Microvascular Dysfunction: Activity of a Micronized Purified Flavonoid Fraction Journal of Vascular Research. ,vol. 36, pp. 15- 23 ,(1999) , 10.1159/000054070
Eliete Bouskela, Kossi A. Donyo, Effects of oral administration of purified micronized flavonoid fraction on increased microvascular permeability induced by various agents and on ischemia/reperfusion in the hamster cheek pouch. Angiology. ,vol. 48, pp. 391- 399 ,(1997) , 10.1177/000331979704800503
I.S. Jamall, V.N. Finelli, S.S. Que Hee, A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Analytical Biochemistry. ,vol. 112, pp. 70- 75 ,(1981) , 10.1016/0003-2697(81)90261-X
M Salucci, L A Stivala, G Maiani, R Bugianesi, V Vannini, Flavonoids uptake and their effect on cell cycle of human colon adenocarcinoma cells (Caco2) British Journal of Cancer. ,vol. 86, pp. 1645- 1651 ,(2002) , 10.1038/SJ.BJC.6600295
Pandarinathan Chithra, G.B. Sajithlal, Gowri Chandrakasan, Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats Molecular and Cellular Biochemistry. ,vol. 181, pp. 71- 76 ,(1998) , 10.1023/A:1006813510959
Michiel H. J. Verhofstad, Wil P. Lange, Jeroen A. W. M. van der Laak, Albert A. J. Verhofstad, Thijs Hendriks, Microscopic analysis of anastomotic healing in the intestine of normal and diabetic rats. Diseases of The Colon & Rectum. ,vol. 44, pp. 423- 431 ,(2001) , 10.1007/BF02234744