Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy

作者: Rebecca E.A. Stace , Thomas Stiehl , Mark A.J. Chaplain , Anna Marciniak-Czochra , Tommaso Lorenzi

DOI: 10.1051/MMNP/2019027

关键词: Cancer cellEpigeneticsCombination cancer therapyCell growthComputational biologyPhenotypeEvolutionary dynamicsBiologyCellPopulation

摘要: We present a stochastic individual-based model for the phenotypic evolution of cancer cell populations under chemotherapy. In particular, we consider the case of combination cancer …

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