Metastatic Progression of Prostate Cancer and E-Cadherin

作者: Aaron P. Putzke , Aviva P. Ventura , Alexander M. Bailey , Canan Akture , John Opoku-Ansah

DOI: 10.1016/J.AJPATH.2011.03.028

关键词: Prostate cancerCancerMetastasisPathologyCadherinIsogenic human disease modelsBiologyEpithelial–mesenchymal transitionMatrigelCancer researchDU145Pathology and Forensic Medicine

摘要: … levels increase eight- to 10-fold despite persistent ZEB1 … are generated by conversion from E-cadherin–negative cells. … breast cancers to be associated with metastasis to bone, and …

参考文章(60)
Schalken Ja, Isaacs Wb, Aalders Tw, Debruyne Fm, Carter Bs, Karthaus Hf, Schaafsma He, Umbas R, Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Research. ,vol. 52, pp. 5104- 5109 ,(1992)
Theresa P. Pretlow, Thomas G. Pretlow, Saeid B. Amini, Moolky Nagabhushan, Liang Cheng, Expression of E-cadherin in primary and metastatic prostate cancer. American Journal of Pathology. ,vol. 148, pp. 1375- 1380 ,(1996)
Lionel Larue, Véronique Delmas, Stefan Butz, Rolf Kemler, Mara Dominis, Otmar Huber, Christopher Antos, A role for cadherins in tissue formation Development. ,vol. 122, pp. 3185- 3194 ,(1996) , 10.1242/DEV.122.10.3185
Mary E Costantino, Randi P Stearman, Gregory E Smith, Douglas S Darling, Cell-specific phosphorylation of Zfhep transcription factor Biochemical and Biophysical Research Communications. ,vol. 296, pp. 368- 373 ,(2002) , 10.1016/S0006-291X(02)00880-X
Dejuan Kong, Sanjeev Banerjee, Aamir Ahmad, Yiwei Li, Zhiwei Wang, Seema Sethi, Fazlul H. Sarkar, Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLOS ONE. ,vol. 5, ,(2010) , 10.1371/JOURNAL.PONE.0012445
Tisheeka R. Graham, Haiyen E. Zhau, Valerie A. Odero-Marah, Adeboye O. Osunkoya, K. Sean Kimbro, Mourad Tighiouart, Tongrui Liu, Jonathan W. Simons, Ruth M. O'Regan, Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells Cancer Research. ,vol. 68, pp. 2479- 2488 ,(2008) , 10.1158/0008-5472.CAN-07-2559
Paul Mak, Irwin Leav, Bryan Pursell, Donggoo Bae, Xiaofang Yang, Cherie A. Taglienti, Lindsey M. Gouvin, Vishva M. Sharma, Arthur M. Mercurio, ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell. ,vol. 17, pp. 319- 332 ,(2010) , 10.1016/J.CCR.2010.02.030
Tatsuo Tsukamoto, Sanjay K. Nigam, Cell-Cell Dissociation upon Epithelial Cell Scattering Requires a Step Mediated by the Proteasome Journal of Biological Chemistry. ,vol. 274, pp. 24579- 24584 ,(1999) , 10.1074/JBC.274.35.24579
Marcello Guarino, Src signaling in cancer invasion. Journal of Cellular Physiology. ,vol. 223, pp. 14- 26 ,(2009) , 10.1002/JCP.22011
Claire E. Hirst, Elizabeth S. Ng, Lisa Azzola, Anne K. Voss, Tim Thomas, Edouard G. Stanley, Andrew G. Elefanty, Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Developmental Biology. ,vol. 293, pp. 90- 103 ,(2006) , 10.1016/J.YDBIO.2006.01.023