Recent developments in antiangiogenic therapy.
作者： Keith Dredge , Angus G Dalgleish , J Blake Marriott
关键词: Arthritis 、 Cancer 、 Diabetic retinopathy 、 Arteriosclerosis 、 Psoriasis 、 Angiogenesis 、 Medicine 、 Antiangiogenic therapy 、 Drug 、 Oncology 、 Internal medicine 、 Pharmacology
摘要: The use of antiangiogenic therapy is gaining momentum as a novel treatment for number conditions, ranging from cancer to psoriasis. This has stemmed research in the early 1970s showing that formation new blood vessels by pre-existing endothelial cells essential tumour growth and progression. However, although was hailed avenue cancer, initial clinical data have been disappointing. led reassessment strategies proposed increase efficacy these agents this setting. Angiogenesis also implicated other conditions are notoriously difficult treat, such arteriosclerosis, arthritis, psoriasis diabetic retinopathy. Increased understanding angiogenic process, diversity its inducers mediators, appropriate drug schedules with modalities may lead radically regimens man...
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