Epidemiology of NSAID induced gastrointestinal complications.

摘要: Nonsteroidal antiinflammatory drugs (NSAID) are one of the most commonly used classes medications worldwide. It is estimated that more than 30 million people take NSAID daily. Gastrointestinal (GI) complications related to therapy prevalent category adverse drug reactions. Patients with arthritis among frequent users and therefore particularly at risk for these side effects. To evaluate nature NSAID-related GI determine how their frequency can be reduced, a series studies such in patients rheumatic disease have been carried out based on data from Arthritis, Rheumatism, Aging Medical Information System (ARAMIS). This report briefly reviews literature presents recent findings ARAMIS studies, which provide an update published information. addresses whether effects as dyspepsia serve warning symptoms life-threatening describes factors events. also summarizes study investigated H2-receptor antagonists antacids affect development serious complications. In addition, ongoing research topics addressed future described.