Low-dose radiation action: possible implications of bystander effects and adaptive response

作者: Francesca Ballarini , Andrea Ottolenghi

DOI: 10.1088/0952-4746/22/3A/307

关键词: Action (philosophy)Context (language use)Bystander effectRadiation toleranceCancer riskNeuroscienceImmunologyLow Dose RadiationMedicineAdaptive responseWaste Management and DisposalPublic Health, Environmental and Occupational HealthGeneral Medicine

摘要: Several experimental studies performed in the last decade have suggested occurrence of low-dose-specific phenomena such as bystander effect (BE, damage induction cells not directly hit by radiation) and adaptive response (AR, resistance to subsequent irradiation with higher doses). Although underlying mechanisms are still known detail, cellular communication is widely regarded a key factor. BE AR may non-negligible role modulating low-dose radiation effects only cells, but also tissues organs. Whether these would imply an increase or decrease cancer risk open question. In this context few representative findings discussed, focusing on their possible implications for risk.

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