Assessing mechanical properties of tissue phantoms with non-contact optical coherence elastography and Michelson interferometric vibrometry

摘要: Purpose : Elastography is an emerging method for detecting the pathological changes in tissue biomechanical properties caused by various diseases. In this study, we have compared two methods of noncontact optical elastography quantifying Young’s modulus tissue-mimicking agar phantoms concentrations: a laser Michelson interferometric vibrometer and phase-stabilized swept source coherence system. Methods The elasticity was estimated from velocity air-pulse induced elastic waves as measured these techniques. Results results show that both techniques were able to accurately assess samples uniaxial mechanical compression testing. Conclusion significantly more cost-effective, but it cannot directly provide wave temporal profile, nor can offer in-depth information.