Genetic Polymorphism, Telomere Biology and Non-Small Lung Cancer Risk.
作者： Rongrong Wei , Frank T. DeVilbiss , Wanqing Liu
DOI: 10.1016/J.JGG.2015.08.005
关键词: Biology 、 Genome-wide association study 、 Telomerase reverse transcriptase 、 Lung cancer 、 Telomere 、 Carcinogenesis 、 Bioinformatics 、 Oncology 、 Internal medicine 、 Single-nucleotide polymorphism 、 Genetic association 、 Adenocarcinoma
摘要: Recent genome-wide association studies (GWAS) have identified a number of chromosomal regions associated with the risk lung cancer. Of these regions, single-nucleotide polymorphisms (SNPs), especially rs2736100 located in telomerase reverse transcriptase (TERT) gene show unique and significant non-small cell cancer (NSCLC) few subpopulations including women, nonsmokers, East Asians those adenocarcinoma. also linked longer telomere length risk. In this review, we seek to summarize relationship between factors further link underlying biology etiology. We conclude that genetic alleles combined environmental (e.g., less-smoking) physiological (gender age) confer are strong for NSCLC. This linkage may be particularly relevant adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations, as mutations been strongly female gender, less-smoking history, histology Asian ethnicity. By establishing connection, argument is made investigating involvement entities during tumorigenesis
elsevier.com
sci-hub.se 参考文章(115)
Bo Lu, Dong Wook Kim, Dennis E Hallahan, Receptor tyrosine kinase inhibitors as anti-angiogenic agents. Current opinion in investigational drugs. ,vol. 5, pp. 597- 604 ,(2004)
V. Courtney Broaddus editor-in-chief, Murray and Nadel's Textbook of Respiratory Medicine ,(2015)
William H. Resnik, Harrison's Principles of Internal Medicine ,(1950)
P. Kleihues, B. W. Stewart, World Cancer Report ,(2003)
Mitchell J Machiela, Chao Agnes Hsiung, Xiao‐Ou Shu, Wei Jie Seow, Zhaoming Wang, Keitaro Matsuo, Yun‐Chul Hong, Adeline Seow, Chen Wu, H Dean Hosgood III, Kexin Chen, Jiu‐Cun Wang, Wanqing Wen, Richard Cawthon, Nilanjan Chatterjee, Wei Hu, Neil E Caporaso, Jae Yong Park, Chien‐Jen Chen, Yeul Hong Kim, Young Tae Kim, Maria Teresa Landi, Hongbing Shen, Charles Lawrence, Laurie Burdett, Meredith Yeager, I‐Shou Chang, Tetsuya Mitsudomi, Hee Nam Kim, Gee‐Chen Chang, Bryan A Bassig, Margaret Tucker, Fusheng Wei, Zhihua Yin, She‐Juan An, Biyun Qian, Victor Ho Fun Lee, Daru Lu, Jianjun Liu, Hyo‐Sung Jeon, Chin‐Fu Hsiao, Jae Sook Sung, Jin Hee Kim, Yu‐Tang Gao, Ying‐Huang Tsai, Yoo Jin Jung, Huan Guo, Zhibin Hu, Amy Hutchinson, Wen‐Chang Wang, Robert J Klein, Charles C Chung, In‐Jae Oh, Kuan‐Yu Chen, Sonja I Berndt, Wei Wu, Jiang Chang, Xu‐Chao Zhang, Ming‐Shyan Huang, Hong Zheng, Junwen Wang, Xueying Zhao, Yuqing Li, Jin Eun Choi, Wu‐Chou Su, Kyong Hwa Park, Sook Whan Sung, Yuh‐Min Chen, Li Liu, Chang Hyun Kang, Lingmin Hu, Chung‐Hsing Chen, William Pao, Young‐Chul Kim, Tsung‐Ying Yang, Jun Xu, Peng Guan, Wen Tan, Jian Su, Chih‐Liang Wang, Haixin Li, Alan Dart Loon Sihoe, Zhenhong Zhao, Ying Chen, Yi Young Choi, Jen‐Yu Hung, Jun Suk Kim, Ho‐Il Yoon, Qiuyin Cai, Chien‐Chung Lin, In Kyu Park, Ping Xu, Jing Dong, Christopher Kim, Qincheng He, Reury‐Perng Perng, Takashi Kohno, Sun‐Seog Kweon, Chih‐Yi Chen, Roel CH Vermeulen, Junjie Wu, Wei‐Yen Lim, Kun‐Chieh Chen, Wong‐Ho Chow, Bu‐Tian Ji, John KC Chan, Minjie Chu, Yao‐Jen Li, Jun Yokota, Jihua Li, Hongyan Chen, Yong‐Bing Xiang, Chong‐Jen Yu, Hideo Kunitoh, Guoping Wu, Li Jin, Yen‐Li Lo, Kouya Shiraishi, Ying‐Hsiang Chen, Hsien‐Chih Lin, Tangchun Wu, Maria Pik Wong, Yi‐Long Wu, Pan‐Chyr Yang, Baosen Zhou, Min‐Ho Shin, Joseph F Fraumeni Jr, Wei Zheng, Dongxin Lin, Stephen J Chanock, Nathaniel Rothman, Qing Lan, None, Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never‐smoking women in Asia: a report from the female lung cancer consortium in Asia International Journal of Cancer. ,vol. 137, pp. 311- 319 ,(2015) , 10.1002/IJC.29393
Daniele Campa, Cosmeri Rizzato, Rachael Stolzenberg-Solomon, Paola Pacetti, Pavel Vodicka, Sean P. Cleary, Gabriele Capurso, H. Bas Bueno-de-Mesquita, Jens Werner, Maria Gazouli, Katja Butterbach, Audrius Ivanauskas, Nathalia Giese, Gloria M. Petersen, Paola Fogar, Zhaoming Wang, Claudio Bassi, Miroslav Ryska, George E. Theodoropoulos, Charles Kooperberg, Donghui Li, William Greenhalf, Claudio Pasquali, Thilo Hackert, Charles S. Fuchs, Beatrice Mohelnikova-Duchonova, Cosimo Sperti, Niccola Funel, Aida Karina Dieffenbach, Nicholas J. Wareham, Julie Buring, Ivana Holcátová, Eithne Costello, Carlo-Federico Zambon, Juozas Kupcinskas, Harvey A. Risch, Peter Kraft, Paige M. Bracci, Raffaele Pezzilli, Sara H. Olson, Howard D. Sesso, Patricia Hartge, Oliver Strobel, Ewa Małecka-Panas, Kala Visvanathan, Alan A. Arslan, Sergio Pedrazzoli, Pavel Souček, Domenica Gioffreda, Timothy J. Key, Renata Talar-Wojnarowska, Aldo Scarpa, Andrea Mambrini, Eric J. Jacobs, Krzysztof Jamroziak, Alison Klein, Francesca Tavano, Franco Bambi, Stefano Landi, Melissa A. Austin, Ludmila Vodickova, Hermann Brenner, Stephen J. Chanock, Gianfranco Delle Fave, Ada Piepoli, Maurizio Cantore, Wei Zheng, Brian M. Wolpin, Laufey T. Amundadottir, Federico Canzian, TERT gene harbors multiple variants associated with pancreatic cancer susceptibility International Journal of Cancer. ,vol. 137, pp. 2175- 2183 ,(2015) , 10.1002/IJC.29590
Beatrice S Melin, Katarina Nordfjäll, Ulrika Andersson, Göran Roos, hTERT Cancer Risk Genotypes Are Associated With Telomere Length Genetic Epidemiology. ,vol. 36, pp. 368- 372 ,(2012) , 10.1002/GEPI.21630
Adi F. Gazdar, Shinichi Toyooka, Kazunori Tsukuda, Mitsune Tanimoto, Masahiro Tabata, Kouichi Ichimura, Masaaki Yano, Toshihide Tsuda, Hisayuki Shigematsu, Hiroshi Date, Kunitoshi Tomii, Nobuyoshi Shimizu, Hiroshi Ueoka, Motoi Aoe, Masaki Tokumo, Katsuyuki Kiura, The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers Clinical Cancer Research. ,vol. 11, pp. 1167- 1173 ,(2005)
Zoraida Verde, Luis Reinoso-Barbero, Luis Chicharro, Nuria Garatachea, Pilar Resano, Ignacio Sánchez-Hernández, Jose Miguel Rodríguez González-Moro, Fernando Bandrés, Catalina Santiago, Félix Gómez-Gallego, Effects of cigarette smoking and nicotine metabolite ratio on leukocyte telomere length. Environmental Research. ,vol. 140, pp. 488- 494 ,(2015) , 10.1016/J.ENVRES.2015.05.008
EUN YOUNG BAE, SHIN YUP LEE, BONG KYOON KANG, EUN JIN LEE, YI YOUNG CHOI, HYO-GYOUNG KANG, JIN EUN CHOI, HYO-SUNG JEON, WON KEE LEE, SHIN KAM, KYUNG MIN SHIN, GUANG JIN, SEUNG SOO YOO, JAEHEE LEE, SEUNG ICK CHA, CHANG HO KIM, TAE HOON JUNG, JAE YONG PARK, Replication of results of genome‐wide association studies on lung cancer susceptibility loci in a Korean population Respirology. ,vol. 17, pp. 699- 706 ,(2012) , 10.1111/J.1440-1843.2012.02165.X