Phylogenetic distribution of plant snoRNA families

摘要: Small nucleolar RNAs (snoRNAs) are one of the most ancient families amongst non-protein-coding RNAs. They ubiquitous in Archaea and Eukarya but absent bacteria. Their main function is to target chemical modifications ribosomal fall into two classes, box C/D snoRNAs H/ACA snoRNAs, which clearly distinguished by conserved sequence motifs type modification that they govern. Similarly microRNAs, appear distinct homologs affect homologous targets. In animals, their evolution have been studied much detail. plants, however, has attracted comparably little attention. order chart phylogenetic distribution individual snoRNA we applied a sophisticated approach for identifying known plant across kingdom. response relatively fast information on boxes, sequences, secondary structure combined identify additional snoRNAs. We identified 296 24 species traced throughout Many comprise paralogs. also found targets well-conserved families. The conservation sufficient establish homologies between phyla. degree this tapers off, land plants algae. Plant frequently organized highly spatial clusters. As resource further investigations provide carefully curated annotated alignments each family under investigation.