Cellular repair factors influencing radiocurability of human malignant tumours
作者： R R Weichselbaum , A Schmit , J B Little
DOI: 10.1038/BJC.1982.2
关键词: Cancer research 、 Glioblastoma 、 Radiation tolerance 、 Cell culture 、 Cell survival 、 Osteosarcoma 、 Pathology 、 Melanoma 、 Neuroblastoma 、 Biology
摘要: We have studied the repair of X-ray-induced, potentially lethal damage (PLD) in 9 human tumour lines derived from tumours varying radiocurability. Cells 3 considered non-radiocurable (1 osteosarcoma, 2 melanoma) repaired significantly more X-ray PLD than cells radiocurable (2 breast, 1 neuroblastoma). The remaining were intermediate their ability for repair, and included another a hypernephroma glioblastoma. conclude that may be an important cellular determinant clinical
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