EF-Hand Ca2+-Binding Proteins in Neurodegenerative Disorders and their Use as Diagnostic Tools
作者： Claus W. Heizmann , Katharina Braun
DOI: 10.1007/978-3-662-21689-7_6
关键词: Neuroscience 、 S100 protein 、 Calcineurin 、 Calmodulin 、 Chemistry 、 Perforant path 、 EF hand 、 Calbindin 、 Human brain 、 Parvalbumin
摘要: In human brain, parvalbumin, calbindin D-28K, calmodulin, calcineurin and S100 protein have been biochemically characterized (chapter 2) immunocytochemically localized 4). Particular interest has given to alterations of these proteins the morphological changes occurring in cells containing Ca2+-binding as a consequence neurological diseases (see Table 2.1).
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