Structural brain changes in first episode Schizophrenia compared with Fronto-Temporal Lobar Degeneration: a meta-analysis
作者： Bayanne Olabi , Ian Ellison-Wright , Ed Bullmore , Stephen M Lawrie
关键词: Voxel 、 Voxel-based morphometry 、 Pathology 、 Psychology 、 Primary progressive aphasia 、 Semantic dementia 、 Grey matter 、 Uncus 、 Frontotemporal lobar degeneration 、 Brain mapping
摘要: The authors sought to compare gray matter changes in First Episode Schizophrenia (FES) compared with Fronto-Temporal Lobar Degeneration (FTLD) using meta-analytic methods applied neuro-imaging studies. A systematic search was conducted for published, structural voxel-based morphometric MRI studies patients FES or FTLD. Data were combined anatomical likelihood estimation (ALE) determine the extent of decreases and analysed ascertain degree overlap spatial distribution brain both diseases. extracted from 18 (including a total 555 621 comparison subjects) 20 FTLD related disorders 311 431 subjects). similarity two significant (p = 0.001). Gray deficits common included bilateral caudate, left insula uncus regions. There is Degeneration. This may reflect overlapping aetiologies, vulnerability these regions distinct aetio-pathological processes disorders.
biomedcentral.com
springer.com
doaj.org
ed.ac.uk
researchgate.net 参考文章(114)
Korbinian Brodmann, Laurence J. Garey, Brodmann's‘Localisation in the cerebral cortex'/ translated by Laurence J. Garey Smith-Gordon. ,(1994)
D. Bergé, S. Carmona, M. Rovira, A. Bulbena, P. Salgado, O. Vilarroya, Gray matter volume deficits and correlation with insight and negative symptoms in first-psychotic-episode subjects Acta Psychiatrica Scandinavica. ,vol. 123, pp. 431- 439 ,(2011) , 10.1111/J.1600-0447.2010.01635.X
James Gee, Lijun Ding, Zhiyong Xie, Michael Lin, Christian DeVita, Murray Grossman, Alzheimer’s disease and frontotemporal dementia exhibit distinct atrophy-behavior correlates Academic Radiology. ,vol. 10, pp. 1392- 1401 ,(2003) , 10.1016/S1076-6332(03)00543-9
Bruce N. Cuthbert, Sarah E. Morris, Research Domain Criteria: cognitive systems, neural circuits, and dimensions of behavior. Dialogues in clinical neuroscience. ,vol. 14, pp. 29- 37 ,(2012)
Laurence J Garey, Brodmann's localisation in the cerebral cortex ,(1999)
J. Peter H. Burbach, Bert van der Zwaag, Contact in the genetics of autism and schizophrenia Trends in Neurosciences. ,vol. 32, pp. 69- 72 ,(2009) , 10.1016/J.TINS.2008.11.002
Guy B. Williams, Peter J. Nestor, John R. Hodges, Neural correlates of semantic and behavioural deficits in frontotemporal dementia. NeuroImage. ,vol. 24, pp. 1042- 1051 ,(2005) , 10.1016/J.NEUROIMAGE.2004.10.023
Ganesan Venkatasubramanian, Neuroanatomical correlates of psychopathology in antipsychotic-naïve schizophrenia. Indian Journal of Psychiatry. ,vol. 52, pp. 28- 36 ,(2010) , 10.4103/0019-5545.58892
Henning Witthaus, Christian Kaufmann, Georg Bohner, Seza Özgürdal, Yehonala Gudlowski, Jürgen Gallinat, Stephan Ruhrmann, Martin Brüne, Andreas Heinz, Randolf Klingebiel, Georg Juckel, Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls. Psychiatry Research-neuroimaging. ,vol. 173, pp. 163- 169 ,(2009) , 10.1016/J.PSCYCHRESNS.2008.08.002
Stuart M. Pickering-Brown, The complex aetiology of frontotemporal lobar degeneration Experimental Neurology. ,vol. 206, pp. 1- 10 ,(2007) , 10.1016/J.EXPNEUROL.2007.03.017