Antinephrolithiatic and antioxidative efficacy of Dolichos biflorus seeds in a lithiasic rat model.
作者： Sarmistha Saha , Ramtej J. Verma
DOI: 10.3109/13880209.2014.909501
关键词: Traditional medicine 、 Dolichos biflorus 、 Urine 、 Ethylene glycol 、 Oxalate 、 Quercetin 、 Chemistry 、 Calcium oxalate 、 Biochemistry 、 Antioxidant 、 Kidney stones
摘要: AbstractContext: Dolichos biflorus sensu auct non L. (Fabaceae) is widely used for the treatment of kidney stones, leucorrhoea, urinary disorders, and menstrual troubles, known its antioxidant activity.Objectives: To evaluate preventive effect hydro-alcoholic extract seeds (DBE) in ethylene glycol induced nephrolithiasis.Materials methods: In vitro antioxidative capacity DBE was estimated terms reducing power, superoxide radical, 2,2- diphenyl-1-picrylhydrazyl nitric oxide scavenging activity. A validated HPLC method standardization using quercetin as a marker. Adult female Wistar rats were administered with (150 300 mg/kg body weight/day) along (0.75%, v/v) 28 d. The various biochemical parameters measured urine, serum, followed by histochemistry.Results: Ethylene caused significant increase calcium, oxalate, phosphate, total protein urine well kidn...
sci-hub.se 参考文章(68)
John C Piccaro, Thomas E Archie, Robert D Scalley, David R Ferguson, Martin L Smart, Treatment of ethylene glycol poisoning. American Family Physician. ,vol. 66, pp. 807- 812 ,(2002)
S. Sethupathy, A. Kottai Muthu, P. K. Karar, R. Manavalan, Hypolipidemic effect of methanolic extract of Dolichos biflorus Linn. in high fat diet fed rats. Indian Journal of Experimental Biology. ,vol. 43, pp. 522- 525 ,(2005)
S. P. Babhale, D. M. Awari, Vaishali Mute, S. P. Chaudhari, Antilithiatic effect of Achyranthus aspera Linn. leaves extract on ethylene glycol induced nephrolithiasis. Journal of Pharmacy Research. ,vol. 2, pp. 994- 997 ,(2009)
S. Selvakumar, A. J. M. Christina, K. S. Saravanan, B. S. Sundar, K. S. Betanabhatla, Antilithiatic activity of Hibiscus sabdariffa Linn. on ethylene glycol-induced lithiasis in rats NPR Vol.8(1) [January-February 2009]. ,vol. 8, pp. 43- 47 ,(2009)
C. P. Khare, Indian herbal remedies : rational Western therapy, ayurvedic, and other traditional usage, botany Indian herbal remedies: rational Western therapy, Ayurvedic and other traditional usage, botany.. ,(2004)
Vernon L. Singleton, Rudolf Orthofer, Rosa M. Lamuela-Raventós, ANALYSIS OF TOTAL PHENOLS AND OTHER OXIDATION SUBSTRATES AND ANTIOXIDANTS BY MEANS OF FOLIN-CIOCALTEU REAGENT Methods in Enzymology. ,vol. 299, pp. 152- 178 ,(1999) , 10.1016/S0076-6879(99)99017-1
P N Viswanathan, Poonam Kakkar, Ballabh Das, A modified spectrophotometric assay of superoxide dismutase. Indian Journal of Biochemistry & Biophysics. ,vol. 21, pp. 130- 132 ,(1984)
F. Atmani, Y. Slimani, M. Mimouni, B. Hacht, Prophylaxis of calcium oxalate stones by Herniaria hirsuta on experimentally induced nephrolithiasis in rats BJU International. ,vol. 92, pp. 137- 140 ,(2003) , 10.1046/J.1464-410X.2003.04289.X
A. Lewis Farr, Oliver H. Lowry, Rose J. Randall, Nira J. Rosebrough, Protein Measurement with the Folin Phenol Reagent Journal of Biological Chemistry. ,vol. 193, pp. 265- 275 ,(1951)
P P Singh, L B K Singh, S N Prasad, M G Singh, Urolithiasis in Manipur (north eastern region of India). Incidence and chemical composition of stones The American Journal of Clinical Nutrition. ,vol. 31, pp. 1519- 1525 ,(1978) , 10.1093/AJCN/31.9.1519