作者: Ian Olver , David Currow , Christos Karapetis , Gelareh Farshid , Gelareh Farshid
DOI: 10.1111/ECC.13451
关键词: Odds ratio 、 Mastectomy 、 Radiation therapy 、 Cancer registry 、 Internal medicine 、 Logistic regression 、 Systemic therapy 、 Medicine 、 Breast surgery 、 Breast cancer
摘要: OBJECTIVE We investigated treatment and survival by clinical sociodemographic characteristics for service evaluation using linked data. METHOD Data on invasive female breast cancers (n = 13,494) from the South Australian Cancer Registry (2000-2014 diagnoses) were to hospital inpatient, radiotherapy universal health insurance Treatments ≤12 months diagnosis analysed, adjusted odds ratios (aORs) logistic regression, sub-hazard (aSHRs) competing risk regression. RESULTS AND CONCLUSION Five-year disease-specific increased 91% 2010-2014. Most women had surgery (90%), systemic therapy (72%) (60%). Less applied ages 80+ vs <50 years (aOR 0.10, 95% CI 0.05-0.20) TNM stage IV I 0.13, 0.08-0.22). Surgical during study period strongly predicted higher survival. Compared with no surgery, aSHRs 0.31 (95% 0.26-0.36) having breast-conserving 0.49 0.41-0.57) mastectomy 0.42 0.33-0.52) when both types received. Patients aged years lower less treatment. More trial evidence is needed optimise trade-offs between benefits harms in these older women. Survival differences not found residential remoteness marginal socioeconomic status.