Genetic polymorphisms and implications for human diseases.

摘要: After the sequencing of human genome is done, enormous genomic information and high-throughput profiling technologies are used. Increased attention has been paid to applying this knowledge get better understanding inherited diseases complex disorders. Single nucleotide polymorphisms (SNPs) DNA sequence variations that occur when a single in altered SNPs an important tool for study genome. Application analysis disease permits exploration influence genetic on susceptibility, drug sensitivity/resistance, ultimately health care. Databases provide powerful resource association studies try establish relationship between phenotype regions Genomic approaches have garnered so much investment because they offer potential factors disease, as well more-precise definitions non-genetic involved.