DNA Pooling: a tool for large-scale association studies
作者： Pak Sham , Joel S. Bader , Ian Craig , Michael O'Donovan , Michael Owen
DOI: 10.1038/NRG930
关键词:
摘要: … approaches listed above in DNA pooling — cleavage, primer extension and hybridization. The main problem that affects cleavage-based methods is … association test statistics 63,64 . In …
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researchgate.net 参考文章(79)
Jon Wasson, Gary Skolnick, Latisha Love-Gregory, M. Alan Permutt, Assessing allele frequencies of single nucleotide polymorphisms in DNA pools by Pyrosequencing™ technology BioTechniques. ,vol. 32, pp. 1144- 1152 ,(2002) , 10.2144/02325DD04
G. Breen, D. Harold, S. Ralston, D. Shaw, D. St. Clair, Determining SNP allele frequencies in DNA pools. BioTechniques. ,vol. 28, pp. 464- 470 ,(2000) , 10.2144/00283ST03
Lon R Cardon, John I Bell, None, Association study designs for complex diseases Nature Reviews Genetics. ,vol. 2, pp. 91- 99 ,(2001) , 10.1038/35052543
W J Ewens, R S Spielman, R E McGinnis, Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). American Journal of Human Genetics. ,vol. 52, pp. 506- 516 ,(1993)
Neil J. Risch, Searching for genetic determinants in the new millennium Nature. ,vol. 405, pp. 847- 856 ,(2000) , 10.1038/35015718
Robert Plomin, Linzy Hill, Ian W. Craig, Peter McGuffin, Shaun Purcell, Pak Sham, David Lubinski, Lee A. Thompson, Paul J. Fisher, Dragana Turic, Michael J. Owen, A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups. Behavior Genetics. ,vol. 31, pp. 497- 509 ,(2001) , 10.1023/A:1013385125887
Charles H. Langley, Anthony D. Long, The Power of Association Studies to Detect the Contribution of Candidate Genetic Loci to Variation in Complex Traits Genome Research. ,vol. 9, pp. 720- 731 ,(1999) , 10.1101/GR.9.8.720
P. Sham, Nicholas John Craddock, Nigel Melville Williams, Michael John Owen, George Kirov, Pooled genotyping of microsatellite markers in parent-offspring trios. Genome Research. ,vol. 10, pp. 105- 115 ,(2000) , 10.1101/GR.10.1.105
Andreas Braun, Daniel P Little, Hubert Köster, Detecting CFTR gene mutations by using primer oligo base extension and mass spectrometry Clinical Chemistry. ,vol. 43, pp. 1151- 1158 ,(1997) , 10.1093/CLINCHEM/43.7.1151
Joseph G. Hacia, Bryan Sun, Nathaniel Hunt, Keith Edgemon, Deborah Mosbrook, Christiane Robbins, Stephen P.A. Fodor, Danilo A. Tagle, Francis S. Collins, Strategies for Mutational Analysis of the Large Multiexon ATM Gene Using High-Density Oligonucleotide Arrays Genome Research. ,vol. 8, pp. 1245- 1258 ,(1998) , 10.1101/GR.8.12.1245