Paper based point-of-care testing disc for multiplex whole cell bacteria analysis.

作者: Chen-zhong Li , Katherine Vandenberg , Shradha Prabhulkar , Xuena Zhu , Lisa Schneper

DOI: 10.1016/J.BIOS.2011.04.035

关键词: BiosensorMultiplexColloidal goldNanotechnologyPaper basedBiomedical engineeringComputer scienceSample (material)Point-of-care testingWhole cellBacteria

摘要: Point-of-care testing (POCT) of infectious bacterial agents offers substantial benefits for disease diagnosis, mainly by shortening the time required to obtain results and by making the test available bedside or at remote care centers. Immunochromatographic lateral flow biosensors offer a low cost, highly sensitive platform for POCT. In this article, we describe the fabrication and testing of a multiplex immuno-disc sensor for the specific detection of Pseudomonas aeruginosa and Staphylococcus aureus. Antibody conjugated gold …

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