VEGF-A clinical significance in gastric cancers: Immunohistochemical analysis of a wide Italian cohort

作者: Elena Lastraioli , Luca Boni , MARIA RAFFAELLA Romoli , Silvia Crescioli , Antonio Taddei

DOI: 10.1016/J.EJSO.2014.03.028

关键词: MedicinePathologicalInternal medicineVEGF receptorsPathologyCohortMultivariate analysisUnivariateImmunohistochemistryCancerOncologyClinical significance

摘要: Abstract Purpose The clinical significance of VEGF-A expression in gastric cancer (GC) has been reported with contradicting results. We analyzed the and a wide Italian cohort GC specimens. Methods was tested by immunohistochemistry 507 patients all stages. impact on overall survival (OS) evaluated conjunction pathological parameters. Results In we studied not an independent prognostic factor neither at univariate nor multivariate analysis. Conclusions Although frequently expressed, our study able to discriminate between groups different risk.

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