Diagnosis of EML4-ALK Translocation With FISH, Immunohistochemistry, and Real-time Polymerase Chain Reaction in Patients With Non-Small Cell Lung Cancer.
作者： Graciela Cruz-Rico , Alejandro Avilés-Salas , Manuel Segura-González , Ana María Espinosa-García , Laura Alejandra Ramírez-Tirado
DOI: 10.1097/COC.0000000000000213
关键词: Medicine 、 Cell 、 Lung cancer 、 Fluorescence in situ hybridization 、 Adenocarcinoma 、 Cancer research 、 Immunohistochemistry 、 Anaplastic lymphoma kinase 、 Polymerase chain reaction 、 Real-time polymerase chain reaction 、 Pathology
摘要: Objective:To assess anaplastic lymphoma kinase (ALK) rearrangement detection with immunohistochemistry (IHC) and real-time polymerase chain reaction (RT-qPCR) in comparison fluorescence situ hybridization (FISH).Methods:Tumor tissue samples from 230 patients advanced non–small cell lung
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