Synthetic lethal targeting of glucose transport

作者: Amato Giaccia , Olga Razorenova , Raymond Tabibiazar , Connie Sun , John Irwin

DOI:

关键词: GLUT1Glucose transporterBiochemistryBiology

摘要: The present invention provides methods for inhibiting growth and proliferation of HIF pathway proficient cells by administering GLUT1 inhibitors the to cells.

参考文章(9)
Kenneth W. Dobie, Scott W. Henry, Eric G. Marcusson, Youngsoo Kim, Modulation of HIF-1 beta expression ,(2005)
Craig Marhefka, Jingrong Cao, Huai Gao, Jeremy Green, Compositions useful as inhibitors of rock and other protein kinases ,(2003)
Curtis Harwig, Maria Rosaria Di Fluri, Al Kaller, Jason Crawford, David Bogucki, Yuanxi Zhou, Christopher Dennis Smith, Siqiao Nan, Gary Bridger, Trevor R. Wilson, Renato Skerlj, Ernest J. McEachern, Dominique Schols, Bern Atsma, Chemokine receptor binding heterocyclic compounds ,(2001)
Suzanne Dawn Rogers, James Donovan Best, Human facilitative glucose transport protein GLUT8 ,(2003)