A concise, palladium-catalyzed approach to (±)-lysergic acid
作者： Sandro Cacchi , Pier Giuseppe Ciattini , Enrico Morera , Giorgio Ortar
DOI: 10.1016/0040-4039(88)85101-3
关键词: Lysergic acid 、 Palladium 、 Olefin fiber 、 Catalysis 、 Chemistry 、 Ketone 、 Carboxylic acid 、 Organic chemistry 、 Vinyl triflate 、 Chemical coupling
摘要: A new and straightforward route to (±)-lysergic acid (1) from the tricyclic ketone 2 is described involving palladium-catalyzed coupling of vinyl triflate 3 with olefin 15 as key step.
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