The Role of Immune Complexes in the Pathogenesis of Pleural Effusions1–3

作者: Brian S. Andrews , Steven K. Goldberg , Narinder S. Arora , John S. Davis , Michael F. Shadforth

DOI: 10.1164/ARRD.1981.124.2.115

关键词: PathogenesisProperdin factor bConnective tissueImmune complexImmune systemPathologyImmune complex formationConnective tissue diseaseMedicineDirect fluorescent antibody

摘要: Thirty-two patients with pleural effusions (7 malignant, 5 connective tissue disease, infections, 9 idiopathic, 6 miscellaneous) were studied to determine if immune complex formation might be involved in the pathogenesis of fluid formation. Immune complexes detected serum, and parietal capillaries using direct immunofluorescence following groups: malignant disease (57%, 29%, 67%), diseases (100%, 100%, 100%), infectious (0%, 44%, idiopathic (67%, 75%), miscellaneous (25%, 17%, 0%). Whereas degree was higher serum than converse true diseases. Activation C3 properdin factor B almost invariable from bacterial infections. These data suggested that are frequently associated exudative pleural...

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