Efficient estimation of disease odds ratios for follow-up genetic association studies.

作者: Jiyuan Hu , Wei Zhang , Xinmin Li , Dongdong Pan , Qizhai Li

DOI: 10.1177/0962280217741771

关键词: EstimationConditional likelihoodDiseaseFollow up studiesOdds ratioStatisticsGenetic associationShrinkage estimatorMedicineSelection bias

摘要: In the past decade, genome-wide association studies have identified thousands of susceptible variants associated with complex human diseases and traits. Conducting follow-up genetic stu...

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