Antidepressant Therapy in Children and Adolescents

作者: Domenic A. Ciraulo , Danielle M. Ciraulo , Glenn Saxe

DOI: 10.1007/978-1-59259-792-5_10

关键词: Clinical trialPharmacotherapyMajor depressive disorderAntidepressantPsychosocialIntervention (counseling)MedicinePsychiatryAnxiety disorderContext (language use)

摘要: In this chapter, we present an overview of antidepressant pharmacotherapy for depressive disorders in children and adolescents. Our intended audience is the generalist, who may be called on to treat older adolescents whom demarcation between adulthood adolescence not clear-cut. From vantage point clinical psychopharmacologist treats adults, several areas require special attention adolescents, including (a) recognition, diagnosis, differential diagnosis; (b) selection psychosocial intervention used with pharmacotherapy; (c) dosing strategies based pharmacokinetics pharmacodynamics; (d) context common comorbid conditions; (e) duration therapy. One most startling differences fields adult childhood therapy relative paucity research data from trials that can make informed decisions.

参考文章(62)
Karen Dineen Wagner, Paroxetine treatment of mood and anxiety disorders in children and adolescents. Psychopharmacology Bulletin. pp. 167- 175 ,(2003)
Talma Hendler, Joseph Zohar, Yehuda Sasson, Miriam Chopra, Iulian Iancu, Michal Lustig, Epidemiology of Obsessive-Compulsive Disorder: A World View The Journal of Clinical Psychiatry. ,vol. 58, pp. 7- 10 ,(1997)
P Hazell, D O’connell, D Heathcote, D Henry, Tricyclic drugs for depression in children and adolescents Cochrane Database of Systematic Reviews. ,vol. 2002, ,(2013) , 10.1002/14651858.CD002317.PUB2
Ronald A. Thisted, Joseph Biederman, Neal D. Ryan, Laurence L. Greenhill, Estimation of the association between desipramine and the risk for sudden death in 5- to 14-year-old children. The Journal of Clinical Psychiatry. ,vol. 56, pp. 87- 93 ,(1995)
Gerald L. Klerman, Increasing Rates of Depression JAMA: The Journal of the American Medical Association. ,vol. 261, pp. 2229- 2235 ,(1989) , 10.1001/JAMA.1989.03420150079041
Javad H. Kashani, Depression in a Sample of 9-Year-Old Children Archives of General Psychiatry. ,vol. 40, pp. 1217- 1223 ,(1983) , 10.1001/ARCHPSYC.1983.01790100063009
Frank W. Putnam, Jaclyn E. Hulsmann, Pharmacotherapy for survivors of childhood trauma. Seminars in Clinical Neuropsychiatry. ,vol. 7, pp. 129- 136 ,(2002) , 10.1053/SCNP.2002.31792
CARROLL W. HUGHES, GRAHAM J. EMSLIE, M. LYNN CRISMON, KAREN DINEEN WAGNER, BORIS BIRMAHER, BARBARA GELLER, STEVEN R. PLISZKA, NEAL D. RYAN, MICHAEL STROBER, MADHUKAR H. TRIVEDI, MARCIA G. TOPRAC, ANDREW SEDILLO, MARIA E. LLANA, MOLLY LOPEZ, A. JOHN RUSH, The Texas Children's Medication Algorithm Project: report of the Texas Consensus Conference Panel on Medication Treatment of Childhood Major Depressive Disorder. Journal of the American Academy of Child and Adolescent Psychiatry. ,vol. 38, pp. 1442- 1454 ,(1999) , 10.1097/00004583-199911000-00020
JEFFREY ALDERMAN, ROBERT WOLKOW, MENGER CHUNG, HUGH F. JOHNSTON, Sertraline treatment of children and adolescents with obsessive-compulsive disorder or depression: Pharmacokinetics, tolerability and efficacy Journal of the American Academy of Child and Adolescent Psychiatry. ,vol. 37, pp. 386- 394 ,(1998) , 10.1097/00004583-199804000-00016
Graham J Emslie, A John Rush, Warren A Weinberg, Robert A Kowatch, Carroll W Hughes, Tom Carmody, Jeanne Rintelmann, A Double-blind, Randomized, Placebo-Controlled Trial of Fluoxetine in Children and Adolescents With Depression Archives of General Psychiatry. ,vol. 54, pp. 1031- 1037 ,(1997) , 10.1001/ARCHPSYC.1997.01830230069010